Our goal is to identify and develop therapeutic solutions for orphan diseases, which currently lack adequate pharmaceutical treatments.A rare disease is defined in Europe as one that affects fewer than one in 2,000 people.<\/p>\n
(Source: [https:\/\/www.iss.it\/malattie-rare<\/a>])<\/em><\/p>\n[\/vc_column_text][divider line_type=”No Line” custom_height=”122″ custom_height_phone=”30px” custom_height_tablet=”60px”][image_with_animation image_url=”446″ image_size=”full” animation_type=”entrance” animation=”Fade In” hover_animation=”none” constrain_group_2=”yes” constrain_group_4=”yes” constrain_group_6=”yes” alignment=”” border_radius=”none” box_shadow=”none” image_loading=”default” max_width=”100%” max_width_mobile=”default” margin_left=”20%” margin_right=”20%” margin_left_tablet=”15%” margin_right_tablet=”15%” margin_left_phone=”2%” margin_right_phone=”2%”][divider line_type=”No Line” custom_height=”122″ custom_height_phone=”30px” custom_height_tablet=”60px”][vc_column_text]\n Our current focus is on two serious rare conditions:\u00a0 <\/span>SBS<\/strong> (Short Bowel Syndrome) and CDD<\/strong> (Congenital Diarrheal Disorders), Microvillus Inclusion Disease (MVID<\/strong>) in particular. SBS is caused by a reduced intestinal surface area needed for the absorption of fluids and nutrients.<\/p>\n[\/vc_column_text][vc_row_inner equal_height=”yes” content_placement=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”column_reverse” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”padding-8-percent” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”right” column_element_spacing=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” advanced_gradient_angle=”0″ gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”7\/12″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” gradient_type=”default”][vc_column_text]\n CDD refers to a group of rare inherited enteropathies characterized by severe chronic diarrhea in the first months of life. One example is MVID, a particularly severe form of CDD, often associated with intestinal failure and dependency on parenteral nutrition from birth.<\/p>\n Both SBS and CDD often cause chronic diarrhea, severe dehydration, metabolic acidosis or alkalosis, and malnutrition\u2014symptoms that can arise quickly and become life-threatening.<\/p>\n[\/vc_column_text][\/vc_column_inner][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_spacing=”default” centered_text=”true” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” advanced_gradient_angle=”0″ gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”5\/12″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” gradient_type=”default”][image_with_animation image_url=”744″ image_size=”full” animation_type=”entrance” animation=”Fade In” hover_animation=”none” alignment=”center” border_radius=”none” box_shadow=”none” image_loading=”default” max_width=”custom” max_width_custom_tablet=”400px”][\/vc_column_inner][\/vc_row_inner][vc_column_text]\n It is estimated that SBS affects between 1 and 9 per 100,000 people. (Sources: orpha.net<\/a> | sigenp.org<\/a>)<\/p>\n There are currently no official sources available for the prevalence of MVID.<\/em><\/p>\n[\/vc_column_text][divider line_type=”No Line” custom_height=”122″ custom_height_phone=”30px” custom_height_tablet=”60px”][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":" [vc_row type=”full_width_background” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” bg_image=”1218″ bg_position=”center center” background_image_loading=”default” bg_repeat=”no-repeat” scene_position=”center” top_margin=”-116″ bottom_margin=”200px” bottom_margin_tablet=”100″ bottom_margin_phone=”60″ text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” advanced_gradient_angle=”0″ overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=”curve”][vc_column column_padding=”padding-8-percent”…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1294","page","type-page","status-publish"],"yoast_head":"\n