{"id":1292,"date":"2022-08-04T11:52:20","date_gmt":"2022-08-04T09:52:20","guid":{"rendered":"https:\/\/napotherapeutics.com\/chi-siamo\/"},"modified":"2025-12-17T09:46:28","modified_gmt":"2025-12-17T08:46:28","slug":"about-us","status":"publish","type":"page","link":"https:\/\/napotherapeutics.com\/en\/about-us\/","title":{"rendered":"About us"},"content":{"rendered":"[vc_row type=”full_width_background” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” bg_image=”1483″ bg_position=”center bottom” background_image_loading=”default” bg_repeat=”no-repeat” scene_position=”center” top_margin=”-116″ bottom_margin=”130px” bottom_margin_tablet=”80″ bottom_margin_phone=”40″ text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” advanced_gradient_angle=”0″ overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=”curve”][vc_column column_padding=”padding-8-percent” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”left-right” column_element_spacing=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” advanced_gradient_angle=”0″ gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” tablet_text_alignment=”default” phone_text_alignment=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” gradient_type=”default”][divider line_type=”No Line” custom_height=”40vh” custom_height_tablet=”400px” custom_height_phone=”200px”][image_with_animation image_url=”1313″ image_size=”full” animation_type=”entrance” animation=”None” hover_animation=”none” alignment=”center” border_radius=”none” box_shadow=”none” image_loading=”default” max_width=”100%” max_width_mobile=”default” translate_y_desktop=”25%”][\/vc_column][\/vc_row][vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” class=”custom-row-padding” advanced_gradient_angle=”0″ overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_spacing=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” tablet_text_alignment=”default” phone_text_alignment=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][divider line_type=”No Line” custom_height=”140″ custom_height_phone=”40″][vc_column_text]\n

We are Napo Therapeutics<\/strong>: an independent European pharmaceutical company headquartered in Milan, a start-up led by a team of experienced professionals. Our mission is to improve the quality of life for people affected by rare diseases and conditions with high unmet medical need through innovative solutions.<\/p>\n[\/vc_column_text][divider line_type=”No Line” custom_height=”122″ custom_height_phone=”30px”][vc_row_inner equal_height=”yes” content_placement=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” text_align=”left” row_position=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” pointer_events=”all”][vc_column_inner column_padding=”padding-8-percent” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”right” column_element_spacing=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” advanced_gradient_angle=”0″ gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/2″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid” gradient_type=”default”][image_with_animation image_url=”86″ image_size=”full” animation_type=”entrance” animation=”Fade In” hover_animation=”none” alignment=”” border_radius=”none” box_shadow=”none” image_loading=”default” max_width=”100%” max_width_mobile=”default”][\/vc_column_inner][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_spacing=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/2″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text]\n

Our name reflects our history: the Napo River flows through the Amazon rainforest, where the Croton lechleri <\/i> plant grows\u2014the source of the sap from which we extract a valuable active compound.<\/p>\n

We are developing an innovative, first-in-class drug based on its mechanism of action, with the goal of gaining marketing authorization across Europe.<\/p>\n

Currently, our focus is on two serious rare diseases: Short Bowel Syndrome (SBS<\/strong>) and\u00a0 <\/span>Congenital Diarrheal Disorders (CDD<\/strong>), including Microvillus Inclusion Disease (MVID<\/strong>).<\/p>\n

Our majority shareholder is Napo Pharmaceuticals, a wholly owned subsidiary of Jaguar Health, headquartered in San Francisco and listed on NASDAQ (JAGX<\/strong>).<\/p>\n[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][divider line_type=”No Line” custom_height=”122″ custom_height_phone=”30px” custom_height_tablet=”80px”][\/vc_column][\/vc_row][vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” class=”custom-row-padding” advanced_gradient_angle=”0″ overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” 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For over 20 years, we have worked closely with local communities and research institutions in the Peruvian Amazon to develop a sustainable model for cultivating and harvesting Croton lechler<\/i>i, a tropical plant known for centuries as *Sangre de Drago*\u2014*Dragon\u2019s Blood<\/strong>*\u2014due to its red sap traditionally used by indigenous populations to treat wounds and gastrointestinal ailments.<\/p>\n[\/vc_column_text][\/vc_column_inner][vc_column_inner column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_spacing=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/2″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][image_with_animation image_url=”91″ image_size=”custom” animation_type=”entrance” animation=”Fade In” hover_animation=”none” alignment=”center” border_radius=”none” box_shadow=”none” image_loading=”default” max_width=”custom” max_width_custom=”60%” max_width_custom_tablet=”70%” max_width_custom_phone=”100%”][\/vc_column_inner][\/vc_row_inner][divider line_type=”No Line” custom_height=”50px”][\/vc_column][\/vc_row][vc_row type=”full_width_background” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” bg_image=”1485″ bg_position=”center center” background_image_loading=”default” bg_repeat=”no-repeat” scene_position=”center” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” advanced_gradient_angle=”0″ overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_spacing=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” tablet_text_alignment=”default” phone_text_alignment=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][divider line_type=”No Line” custom_height=”500px”][\/vc_column][\/vc_row][vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” class=”custom-row-padding” advanced_gradient_angle=”0″ overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_spacing=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” tablet_text_alignment=”default” phone_text_alignment=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][divider line_type=”No Line” custom_height=”110″][vc_custom_heading text=”The harvest of Croton lechleri” font_container=”tag:h5|text_align:left|color:%23000000″ use_theme_fonts=”yes”][divider line_type=”No Line” custom_height=”54″]

\n

Croton lechleri<\/i><\/strong> grows naturally in the rainforests of Venezuela, Colombia, Peru, Bolivia, Ecuador, and Brazil, especially along the Napo and Pichis River basins.<\/p>\n

From the 1980s onward, areas such as the Pichis valleys\u2014home to the Ash\u00e1ninka, Y\u00e1nesha, and Cacataibo peoples\u2014began to experience migration and land-use conflicts, including coca leaf cultivation. Governments and NGOs continue to work with communities to promote crop substitution and social development.<\/p>\n

In response to these challenges, Jaguar Health and Napo launched a collaboration in the early 2000s with local producers and communities to support the sustainable wild collection of Croton lechleri<\/i>, aiming to ensure the long-term resilience of this medicinal plant for the benefit of patients, local producers, indigenous groups, and the ecosystem.<\/p>\n

We developed a method combining wild collection, reforestation, and low-impact cultivation.<\/p>\n

The sap is only extracted from trees specifically planted and sustainably grown. The collection method maximizes resin yield and promotes natural soil regeneration in degraded forest areas.<\/p>\n <\/div>[divider line_type=”No Line” custom_height=”54″][\/vc_column][\/vc_row][vc_row type=”full_width_background” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” bg_image=”1477″ bg_position=”center center” background_image_loading=”default” bg_repeat=”no-repeat” scene_position=”center” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” advanced_gradient_angle=”0″ overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_spacing=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” tablet_text_alignment=”default” phone_text_alignment=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][divider line_type=”No Line” custom_height=”500px”][\/vc_column][\/vc_row][vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” class=”custom-row-padding” advanced_gradient_angle=”0″ overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_spacing=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” tablet_text_alignment=”default” phone_text_alignment=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][divider line_type=”No Line” custom_height=”110″][vc_custom_heading text=”Where are the trees planted?” font_container=”tag:h5|text_align:left|color:%23000000″ use_theme_fonts=”yes”][divider line_type=”No Line” custom_height=”54″]

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Croton lechleri<\/i> is a natural soil conditioner. Our sap extraction process enhances its ability to improve soil biology.<\/p>\n

For every harvested tree, we plant at least two or three more. Since 2000, approximately 800,000<\/strong> Croton lechleri<\/i> trees have been planted in seven regions of Peru.<\/p>\n

After sap collection, the felled tree is left on-site to return organic material to the ecosystem, while its seeds are used for reforestation. The sap is delivered, registered, tested, filtered, and packaged for transport.<\/p>\n

This project would not have been possible without the collaboration, experience, and support of local communities and research institutions in Colombia<\/strong>, Ecuador<\/strong>, and Peru<\/strong>.<\/p>\n

Special thanks to the Yanesha and Ashaninka communities of Pichis, the Palcazu valleys, the Awajun, Kichwa, Kandozi\u00a0 <\/span>tribes, and the Maijuna people of Sucusari along the banks of the Napo River.<\/em><\/p>\n <\/div>[\/vc_column][\/vc_row][vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none”][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_spacing=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” tablet_text_alignment=”default” phone_text_alignment=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_raw_html]JTNDZGl2JTIwY2xhc3MlM0QlMjJlbmQtcGFnZS1zcGFjZSUyMiUzRSUzQyUyRmRpdiUzRQ==[\/vc_raw_html][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"

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